Our Verruca Freeze FAQ page.

If you have any questions beyond what is shown here, please feel free to contact us!

1. Why should I choose Verruca-Freeze®?

Verruca-Freeze® is a portable, self-contained cryosurgical unit cleared for the removal of 21 benign skin lesions. It is non-flammable (No Hazmat fees), bloodless, odorless and self-anaesthetizing. This one minute procedure can generate extra revenue for your practice. Cryosurgery with Verruca-Freeze® is easy to learn and 91.3% effective on the first treatment.

2. How can I generate revenue using Verruca-Freeze®

Reimbursements are $100-$250 or more depending on where the lesion is located on the body. (ie. venereal lesions have much higher return rates)

3. How do I choose the right Verruca-Freeze® product for me?

Please see FAQ #7. How many lesions can I treat with a canister of Verruca-Freeze®?

4. Does Verruca-Freeze® have Hazmat fees?

No, Verruca Freeze® is non-flammable with no Hazmat fees.

5. What is the difference between Verruca-Freeze® and Histofreezer®?

Visit our Comparison Page for even more info on how Verruca-Freeze® is different from CryoProbe, CryOmega, CryoPen, and Brymill’s Cry-Ac.

6. What lesions can I treat with a canister of Verruca-Freeze®?
The most recent cryosurgery textbooks state that -50°C is adequate to treat most benign skin lesions. Verruca-Freeze® delivers freezing temperatures of -70°C (-94°F), exceeding the minimum recommended freezing temperatures. The FDA has cleared Verruca-Freeze® for removal of 21 types of lesions including: warts, plantar warts, venereal warts (condyloma acuminatum), seborrheic and actinic keratoses, achrochordon (skin tags), molluscum contagiosum, age spots, dermatofibroma, small keloids, granuloma annulare, porokeratosis plantaris, angiomas, lentigo maligna, keratoacanthoma, lentigo discreta, chondrodermatitis, epithelial nevus, leukoplakia and pyogenic granuloma. Lesion Descriptions
7. How many lesions can I treat with a canister of Verruca-Freeze®?

The number of freezes per canister will depend on the severity of lesions treated. Here is a summary of the amount of freezes you can expect on average from your canister of Verruca-Freeze®:


Introductory Kit 120mL Approx. 45 to 50 freezes
VFK50 and VFC50 150mL Approx. 55 to 60 freezes
VFK65 and VFC65 162mL Approx. 65 to 70 freezes
VFL100 236mL Approx. 100 freezes
VFL200 and VFL200R Two 236mL canisters, 472mL total Approx. 200 freezes
VFL300 Three 236mL canisters, 708mL total Approx. 300 freezes
*Amount of freezes per canister based on usage of the 5mm CryoBud®

Some factors that determine the amount of freezes you will utilize in a canister of cryogen:

  • The size and severity of lesions treated (e.g. large plantar warts)
  • The amount of times the Double-Freeze-Thaw method is employed
  • The pressure which the physician squeezes the trigger

Some physicians increase the number of lesions they treat successfully by combining chemical treatment with cryosurgery. They use salicylic acid after cryo to treat difficult plantar warts and podophyllum after cryo to treat small, invisible venereal warts.

8. What are the methods of application for Verruca-Freeze®?

Verruca-Freeze® has two methods of application: transparent CryoCones®, available in five sizes (3mm, 5mm, 7mm, 9mm, 12mm) and CryoBuds® available in sizes small, medium and large. CryoBuds® are convenient in hard-to-reach or bony areas of the body. CryoBuds® are disposable. They can be used more than once on the same patient, but are not interchangeable between patients.

The CryoCones® are reusable and should be soaked in bactericidal solution for sterilization. CryoCones® can be autoclaved on the lowest setting if desired.

9. What is the recommended freeze time for Verruca-Freeze®?
Verruca Vulgaris 40 seconds 17110
Verruca Plantaris 40 seconds 17110
Age Spots 40 seconds 17000
Genital Lesions 35 – 40 seconds 54056
Skin Tags 35 – 40 seconds 11200
Actinic Keratoses 40 seconds 17000
Verruca Plana 40 seconds 17110
Seborrheic Keratoses 35 – 40 seconds 17000
Lentigo 40 seconds 17110
Molluscum Contagiosum 35 – 40 seconds 17110


Spray time is approximately 3 to 6 seconds. When using the transparent limiting cones, accumulate approximately 1/8th inch (3mm) of cryogen into the cone. When using the CryoBud®, saturate the bud to its first drip point.

Freeze time varies depending on the size, type and depth of the lesion. Freeze time is approximately 20-30 seconds. Allow a thaw time of approximately 40 seconds. We recommend freeze-thaw-freeze on lesions greater than 5mm and plantar warts.

Through our training video, instruction manual and practice media provided with each kit, you will be able to quickly grasp how much of the cryogen to spray. Freeze and thaw times are important in order to achieve success in effectively treating lesions with Verruca-Freeze®

If you feel you have sprayed too much Verruca-Freeze®, let the cryogen spill to the floor, then remove the limiting cone, and place your hand on the lesion to stop the freeze cycle. Always protect the eyes and ears when performing cryosurgery.

10. What is the shelf life of Verruca-Freeze® and how do I store it?

A canister of Verruca-Freeze® has a positive shut off valve which prevents leakage. Due to our positive shutoff valve, Verruca-Freeze has an indefinite shelf life if it is stored in a cool location. The canister should be stored in a room where the temperature does not exceed 100°F and the canister is kept out of direct sunlight.

11. Why should I use Verruca-Freeze® instead of Nitrous oxide?

Nitrous oxide can also be used for cryosurgery and is usually applied with a cryoprobe. To use nitrous oxide a physician must have a gas cylinder, a regulator, a pressure gauge, and a cryogun with assorted tips. While the gas does not evaporate like liquid nitrogen, the cost of the basic tank, without the probes can be between $2,000 and $4,000 with the probes averaging $350 – $400 each. When the tank is empty a refill can run from $75 to $200 a month, plus delivery charges.

Nitrous oxide is a known teratogen. In addition, because of studies done on health care professionals showing adverse health consequences, OSHA requires that all nitrous oxide systems be vented directly outside. This is not practical in many office situations.

12. I use scalpel surgery or electrocautery. Why should I switch?

While these methods of removing a lesion are effective, they are also time consuming and produce medical wastes and/or an unpleasant odor. With Verruca-Freeze®, the procedure takes less than one minute, there is no medical waste, no anaesthetic is required, an assistant is not required, and no bandages are needed. The medical staff is not exposed to HIV or Hepatitis B viruses.

Your average cost-per-freeze is $2.70 - $6.88. If you factor in your time and your staff time into the surgical equation, you can see that scalpel surgery or electrocautery cost much more but both methods are generally reimbursed at or nearly the same rate as cryosurgery.

13. What codes do I use to get the best reimbursement?
Use the 17000 series of CPT codes for destruction of lesions. Some lesions, such as venereal warts are coded by the lesion’s location. Reimbursement varies among insurance carriers and different areas of the country.
Click here For a comprehensive list of CPT Codes, Private Insurance Reimbursements and Medicare Reimbursements for all 50 states.
14. How can I learn more about Verruca-Freeze®?

Contact Cryosurgery, Inc. at 800-729-1624 or info@cryosurgeryinc.com. The National Procedures Institute in Midland, Michigan teaches courses in dermatologic procedures using Verruca-Freeze®, offering classes in different U.S. cities. Contact NPI at 800-462-2492 or at The National Procedures Institute website. The AAFP and the AAPA also conduct dermatology workshops at their annual meetings.

15. How can I clean CryoCones®?

Disinfecting CryoCones® – According to CDC guidelines, CryoCones® are classified as a non-critical medical device and may be disinfected using an EPA registered intermediate-level or low-level disinfectant. CaviCide® or CaviWipes™ by Metrex are highly recommended. Please follow the directions provided by the disinfectant manufacturer.

Cones can be autoclaved on the plastics setting if desired. Refer to autoclave instructions for plastics specifications. Caution: Autoclaving CryoCones® may reduce their shelf life.

16. When to use CryoCones® VS CryoBuds®?

The selection of application method is usually the physicians preference. We do recommend using our CryoBuds® for treating lesions on the head, neck, hands, thin skin, bony areas and when treating small children.

17. Are there any techniques to enhance the treatment?

In addition to our double freeze thaw method, a technique called ballooning is often used. This is often used by podiatrists treating plantar warts and veterinarians treating sarcoids on large animals. This technique involves injecting lidocaine with epinephrine beneath the lesion. This injection does two things. First, it seperates the lesion from the blood supply, and second, it causes vaso constriction of the blood vessels which reduces the heat sink and allows the freeze to penetrate deeper and last longer. By doing this you are separating the lesion from the blood supply which allows the ice ball to penetrate deeper.

18. After purchasing a starter kit do I ever need to purchase another kit?

Although some of our customers go many years without purchasing a new kit, we highly encourage the purchase of additional kits if you wish to treat patients in different exam rooms or at different offices; so you will have all the CryoCones® and CryoBuds® readily available.

It is also our recommendation to purchase a new kit every 3 to 5 canister uses to receive additional cones and bud applicators as well as updated educational and instruction materials. The kits are priced only $20 to $35 more than the individual canisters, and are well worth the cost to update your applicators and educational materials.

19. What is the potential revenue that can be made with Verruca-Freeze® per canister?
Product Per Treatment Average 100% Revenue 75% Revenue 50% Revenue
Introductory Kit (40-45 freezes) x $150 $5,250 $3,938 $2,625
x $175 $6,125 $4,594 $3,062
x $200 $7,000 $5,250 $3,500
50 Freeze Kit or Canister x $150 $7,200 $8,750 $3,750
x $175 $8,750 $6,562 $4,375
x $200 $10,000 $7,500 $5,000
65 Freeze Kit or Canister x $150 $9,750 $7,313 $4,875
x $175 $11,375 $8,531 $5,687
x $200 $13,000 $9,750 $6,500
100 Freeze Canister x $150 $15,000 $11,250 $7,500
x $175 $17,500 $13,125 $8,500
x $200 $20,000 $15,000 $10,000
200 Freeze Twin Pack x $150 $15,000 $22,500 $7,500
x $175 $35,000 $26,250 $17,500
x $200 $40,000 $30,000 $20,000
300 Freeze Triple Pack x $150 $45,000 $33,750 $22,500
x $175 $52,500 $39,375 $26,250
x $200 $60,000 $45,000 $30,000

 Often, multiple superficial lesions (such as skin tags) can be treated with fully charged medium and large CryoBuds®, which can dramatically increase the number of freezes per canister.

20. Does Verruca-Freeze® contain CFCs?


On approval of the Montreal Protocol set into motion to ban all CFCs (Chlorofluorocarbons) production in any form and was ratified by 196 countries. The terms call for zero production of CFCs in the world by 1996. The United States stopped production in 1990.

Any use of CFCs would be considered a violation of the world-wide agreement to ban production and use of Chlorofluorocarbons.




21. What is your cost per freeze compared to CryoProbe & CryOmega?


  • 6+ years shelf life
  • Cost per freeze: $2.70 - $6.88
  • 4 different canister sizes available
  • Number of freezes per canister: 40 – 100, depending on canister size
  • Freezing time: 20 – 40 seconds
  • Can treat multiple lesions on the same patient with CryoBuds®


  • 6 month shelf life once activated
  • Cost per freeze: $14.17 – $21.25
  • 240 seconds spray time
  • 10 – 15 seconds spray per lesion
  • 16 – 24 treatments per Unit


  • Shelf life: “weeks” after punctured
  • Warranty: unknown
  • 120 seconds of freeze time (8g Cartridge)
  • 10 – 15 second spray per lesion
  • Upfront Cost of $2,995 for the X Starter Kit
    • Assume:
      • 3 year life span
      • Average of 100 lesions treated per year
    • Cost Per Treatment (not including the cartridge)
      • 6 mos – 50 lesions: $60 per lesion
      • 1 yrs – 100 lesions: $30 per lesion
      • 2 yrs – 200 lesions: $15 per lesion
      • 3 yrs – 300 lesions: $10 per lesion
22. What are my options for high volume treaments, 50 or more a month?
When treating a high volume of lesions we recommend using our VFL100 Freeze Canister filled with 236ml of cryogen. Our VFL offers an extremely low cost per treatment at $2.70 - $6.88 per freeze. If you are interested in lowering your cost per freeze even more, ask us about our new 200 Freeze Twin Pack & 300 Freeze Triple Pack.



Both the Twin and Triple packs are ideal for large clinics or those treating over 100 lesions a month. Contact us at 615-354-0414 or ask your distributor to give us a call.

23. Tips for Perfecting Cone Freezing Technique
  1. Make sure patient is properly positioned and cone is pressed firmly, covering the lesion.
  2. Gently spray and fill cone a minimum of 1/8th inch (1/4 inch for 3ml or 5ml cones).
  3. Evaporation time should be at least 30 seconds.
  4. Thaw time ideally is between 35 seconds and 40 seconds.
  5. After complete thawing, repeat freeze thaw cycle if thereis any doubt about under freezing.
24. Tips for Perfecting Bud Freezing Technique
  1. Buds can be used anywhere on the body, but especially should be used on the face and neck.
  2. Gently press the trigger to slowly saturate the bud completely, until the first drip.
  3. After saturation, wait 15 to 20 seconds for complete ice crystalization to form inside the bud before application (This is a critical step because the bud temperature will fall an additional 3 to 6 degrees by waiting 15 to 20 seconds).
  4. Press bud firmly to the lesion for 30 to 40 seconds to form a good ice ball.
  5. Remove the bud and allow the lesion to slowly thaw 30 to 40 seconds. Touching the lesions before the thaw is complete can cancel the effect of the freeze.
25. How much do veterinarians typically charge for Verruca-Freeze® treatments?

Typically, veterinarians charge a fee of $50-$75 per treatment without anesthesia. If anesthesia is required, the fees range from $150-$200. If there are multiple lesions to be treated on one patient, some veterinarians will charge a flat fee for the first lesion ($50), and a minimal fee ($10-$12) for each additional lesion.